The development of early reverse osmosis scale inhibitors was affected by Qingli reverse osmosis scale inhibitors, and there were certain defects in the design of the formula. Later, the analysis and performance tests of the reverse osmosis scale inhibitor formulas of other foreign manufacturers were carried out. The formula of reverse osmosis scale inhibitor has been optimized and adjusted to get rid of the concept of "concentrate". The optimized reverse osmosis scale inhibitors are divided into non-phosphorus and phosphorous formulations, and the concentration is 1.5~2.0mg/L when used on site. The scale inhibition performance is at the same level as foreign products, but better than Qingli products.